It's easy advice because it works:

Let's say your tegu got into carpet cleaning solution and is having neurological issues. Someone on the net says it's calcium related and the underlying chemical exposure isn't treated. If the calcium plasma tests are low, then treatment is one way, if they are normal, treatment goes another.

Very little info was given in your original post, so I covered anything that could have happened in two years. It could have been a slowly building issue. What is the diet? What bulbs are you using, when were they replaced last, and how are they positioned? What are the temps? Are they warm enough to facilitate the Vit D synthesis and calcium utilization process? What kind of supplements are you using? Have you switched recently? Do they contain phosphorous with the calcium?

Reread my original response and see if any of those address your husbandry. Then you can try to figure out what happened.

I'm really not trying to sound harsh or come-back-ish...I'm trying to help you solve your issue. It's difficult at time to give Internet advice, especially without any info about husbandry.

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