Could be either RI or a reaction to the PAM treatment. See my post just below on "General rules for small snakes", concerning mite treatment. The procedure I describe in that post can be used just as effectively with larger snakes. Also, did you use the spray for mites this last time you cleaned the cage?

I would stop all mite treatments at this point and observe this python for a few days. Some snakes will be overly active when placed in an unfamiliar new cage, but my concern is the observation of mucous for the second time and the frequent yawning, which are common signs of respiratory irritaion whether it is chemical, mechanical, or bacterial in origin. Did you notice if the mucous was clear or opaque? Also, some pythons will rub their noses when they have an RI due to the nasal irritation and excess mucous. If it is an RI, the excess mucous will not go away in a few days, but if it is a chemical irritation, it most likely will. Obviously if the environmental conditions are good and the symptoms continue, a vet visit may be in order. What was your cage setup before you made the change? Temps, humidity, hide box, etc. Ball pythons are fairly adaptable, and usually husbandry needs to be off a fair amount to cause health issues.

Kelly

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