Have you tried consulting an animal behaviorist? It's worth a shot since you have already tried everything else. There are other behavior modification drugs that your vet can give you for Isis that won't make him foam. I would definitely try some of them. You can also try Feliway with Comfort Zone plug-ins. It calmed down one of my cats who was contantly attacking the others.
Good luck to you. I hope the problem can be resolved so Isis can keep his home.
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Dottie
Proudly owned by The Catnip Crew...Munchkin,Casey,Maddie,Harley,Meadow,Ashley,Nicky and Mushka

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