If the hissing is still going on come Monday, you might think about contacting your vet and seeing if s/he will prescribe an antianxiety drug for the hissy kitty. These very often work wonders - the cat calms down and forgets why he is upset. Then you gradually withdraw the medication under the vet's supervision.

Usually the side effects of these are drowsiness, but with a cat this is not a huge issue! At least not with my cat!

A more natural remedy is Rescue Remedy - folks swear that four drops a day in the drinking water will do the trick - or rub a drop onto the eartip. And Rescue Remedy is safe for humans too - follow the label directions. This is available at most health food/vitamin places.
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Smile, it will make them wonder what you are up to!

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