While it is possible it is some disease, the most likely culprit is husbandry.

Doing well for several weeks, would not lead up to their deaths.

My guess... Bacterial infection gone uncontrolled from a weak immune system, followed by organ failure. The bumps, are puss filled pockets, and are a symptom and not the source.

If you have monitors (or other animals) die of mysterious deaths, that you really need to know the answer to. Bag them, toss them in the fridge (not the freezer), and contact a vet to do a necropsy.

You are taking the fact they died in the same period as meaning something, I would take that they both died in your cage and your conditions to be far more relevant. I'm not trying to be mean, but an inexperienced keeper throwing two different species of monitors together in a small crowded aquarium is a recipe for disaster.

Sorry,

--Robert

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