You could place both lights on timers and save yourself teh trouble of manually truning lights on and off, or worrying about such while vacationing. If such is not a possibility, I would either leave the night light on or the light within the room.
One thing I have always enjoyed about keeping snakes is the luxury of being able to leave for a week and not worry.
Also, I am certain the water within your existing water dish will be plenty for the weekend.

Now, go enjoy your weekend!

jeff
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Jeff Snodgres
University of Arkansas
snodgresjeffreys@uams.edu
501.603.1947

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