Actually MDF will be less moisture resistant than most any plywood, which is why many cabinet companies will use plywood on their sink and vanity base cabinets but then use MDF or particle board for everything else. Unless you mean the waterproof MDF which I understand to be expensive and hard to find. I believe it also offgasses, like other treated materials.



Also, for a cage the size you are thinking of I would have a slight preference for plywood or even melamine.



Regarding easier to clean, either plywood or melamine will need to be sealed and what you use for that will ultimately determine how easy it is to clean.



Still, I think MDF is a decent product for some uses. It's very flat and consistent in thickness. In the past it has been very cheap compared to plywood and melamine, although the last time I checked MDF was close enough to melamine in price that I could not imagine using it. Don't know what prices are like today.
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Currently keeping a small collection of various Gonyosoma. Both G. janseni and G. oxycephala.

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