When was the last time it was fed?

Any signs of respiratory distress such as noisy, raspy breathing?

Without seeing the snake firsthand, what jumps in my mind is respiratory infection, especially with the changing seasons. If the ambient temps in your house have dropped, have you adjusted temps in your house? I'd bump the heat up in her cage a bit just in case, being sure to give her the ability to thermoregulate. If you think there are any signs of RI, I'd take her to a vet as well.

Just my $.02

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