Metabolic bone disease, where a lack of calcium over a period of time causes the animal to take calcium from its skeleton for life functions, or too little calcium for a growing young animal causes the same thing.
If fed a proper diet, they dont have these problems. Many reptiles with MBD are fed commercial diets.
To this day the reptile product industry insists that you need UV bulbs to keep your reptiles alive and healthy, but its a proven fact that these are income generating products, not at all required, and in most cases absolutely useless for what they claim is posible with them.

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