Yea the tightest inbreeding would be full sister to full brother. I think You would be safe to do this 3 times F3's or untill You seen a loss of vigor in some of the babys. I try and line breed rather then inbreed,like Aunt to Nephew or Grand father back to a grand Daughter.. Just remember full sister to brother is the tightest breeding they have the same Genes,where as Mother to Son they would have only half of the same genes.. I hope that helps You out alittle anyway.



Van
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