Posted by:
LarM
at Sat Mar 20 21:37:32 2010 [ Email Message ] [ Show All Posts by LarM ]
I was proposing a possibility in theory.
Most likely Sharp and BWC do reside on the same Loci but if not
This is where my uneducated mind speculates possibly a different process
A process that does not require the two traits to reside on the same Locus
I've been curious if BWC and Sharp affect the Tyrosinase catalyzing enzyme
in a different way creating the Paradigm
I still believe with my scenario when the Sharp Gene and the BWC gene
are combined or unite in any way a Paradigm will result
Leaving no possibility for a Sharp Albino het BWC
I still haven't thought this all the way through so there
are still holes in this idea
It might be as simple as a disruption of the chromatoblasts
migration to the skin early in embryogenesis
Or it might be a disruption somewhere else in the process
Melanophores, found in both the dermis and epidermis, are dendritic cells that synthesize melanin, or black and brown pigments. Melanin is contained in melanosomes, intracellular organelles within the melanophore. Melanosynthesis, the synthesis of melanin, essentially consists of the conversion of the amino acid tyrosine into melanin, through a series of chemical reactions. Tyrosine is first converted to dihydroxyphenylalanine (dopa), and dopa to dopaquinone, in the presence of a catalyst, o-Diphenol oxidase (tyrosinase). Tyrosinase is a copper-protein enzyme, and the conversions of tyrosine and dopa cannot take place in the absence of this catalyst Both the synthesis of melanin and tyrosinase occur in the melanosome. From the melanosomes, synthesized melanin is transferred to the dendrites, projections found on the cell wall, at which point dopaquinone continues to undergo further metabolic elaboration to become melanin (Bechtel, 1995).
Like I said above I'm potentially over looking major facts
that would discount my idea.
. . . Lar M
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RE: Hey Larry Larry Larry Larry & Dr. Booth - LarM, Sat Mar 20 21:37:32 2010