Posted by:
WK
at Sat Oct 11 09:18:18 2003 [ Email Message ] [ Show All Posts by WK ]
Thanks mate. Next time you can just say, “Finish reading the paper I sent you!” Having just done this, I see that you mentioned immunoglobulins / MHC genes and the similarities between these and toxin genes with respect to evolution (bottom of page 118). You also mentioned the analogy between immune system-antigen and snake venom-prey interactions. Believe it or not, my apparent plagiarism in my last post was unintentional. I’m embarrassed!
I plan to get the referenced 1997 Nei paper, and this question may be addressed therein, but I was also wondering if mutations in toxin genes seem to occur more frequently or in a non-random manner in exons coding for surface regions whose residues actually contact the target? If so, could this represent evidence that these sequences are intentionally mucked with to generate diversity?
Cheers,
WK
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