First be sure that you have reservations to stay in pet-friendly motels and that they know you will be bringing the cats. Just recently I was on a trip and the motel I was staying in was advertised as allowing pets. However, all the "pet" rooms were taken and a woman who had arrived with a dog got turned away because she didn't have advanced reservations. Do not go away from the motel room unless both cats are secured in the carriers. Even if you put the do not disturb sign up, a careless motel worker could come in and inadvertently let the cats out.



Second, be sure that both cats have collars and ID tags. They should travel in separate carriers, however, be sure to fasten seat belts around both carriers so they will travel securely. It may be best to have one in the front seat and one in the back so you can access both with the car doors shut. Be sure to have a litterbox handy in the car and stop and allow both cats to have access to it every couple of hours. They probably won't go, but you can try. Also be sure to offer them food and water during their rest breaks.



Try not to leave the cats unattended in the car. Perhaps you can get someone to travel with you so that you can take restroom breaks.



Usually tranquilizing the cats is not a good idea. It is difficult to predict what reaction the cats will have and sometinme tranquilizers can have the reverse effect and make the cats more active and restless.



Check out the Traveling with Cats section on the link below for more info:



link
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Smile, it will make them wonder what you are up to!

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