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RE: How do I prepare FLAGYL for dosage?

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Posted by: oldherper at Tue Nov 23 06:29:16 2004   [ Email Message ] [ Show All Posts by oldherper ]  
   

>>Flagyl (aka metronidazol) comes in a variety of dosage concentrations but if you order it from the health care section of www.beanfarm.com then it will be 250mg/kg of body weight. The scales can be purchased fairly cheeply from office depot. A postage scale will do nicely. Using the medication obtained from the beanfarm, mix one capsule with 5ml (5cc) of deionized water. If it does not desolve readily you may try dissolving it in a nonpolar solution such as 5ml (5cc) of vegetable oil (not to me administered in large amounts)! The medication needs to be fully disolved. This will yeild an oral suspension of 50mg per every 1.0ml (1.0cc) of liquid extracted. At a dosage of 50mg/1kg of body weight, an animal weighing 1kg (or 1,000g) should receive a 1ml (1cc) dosage of the suspension orally. Supposing the animal weighs 0.5kg (500g), then give have the dosage meaning 0.5ml (0.5cc) of the oral suspension.

>>

>>As you can see this is very complicated and risky! Reptiles do not process medication/toxins efficianlt. I have given you this information as general knowlege not intended for use! I do not reccomend doing this yourself! Especially if you lack the experience! It is very easy to overdose your pet and I highly reccomend that you see a veterinarian and that you not attempt this yourself!




Quote:Flagyl (aka metronidazol) comes in a variety of dosage concentrations but if you order it from the health care section of www.beanfarm.com then it will be 250mg/kg of body weight.



I think you meant to write "250mg per capsule", not 250 mg/kg body weight. 250 mg/kg is enough to kill many snakes.



Quote: If it does not desolve readily you may try dissolving it in a nonpolar solution such as 5ml (5cc) of vegetable oil (not to me administered in large amounts)!



Do you have reference to the absorption rates for Metronidazole in reptiles when administered as a suspension in vegetable oil? This may work well in mammals, but I'm not sure I'd recommend it for snakes. Snakes do not digest vegetable matter or oils very well. If the oil passes through the digestive tract undigested, then most of the medicine will be excreted with the oil. Not to mention the fact that Metronidazole is a prodrug that is activated by water. If the particles are coated in oil, it will not dissolve in the water and any that remains in the digestive tract will not activate and will be ineffective.












-----
We do not inherit the Earth from our ancestors; we borrow it from our children. Ralph Waldo Emerson


   

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>> Next Message:  Oldherper, method of metronidazole administration..... - Kelly_Haller, Tue Nov 23 13:26:13 2004

<< Previous Message:  RE: How do I prepare FLAGYL for dosage? - prevetherper, Mon Nov 22 22:36:49 2004

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