People do self-immunize... but on the other hand...
I was just reading a thread, and I can't find it now, but it was about a guy in Europe who worked with vipers, and after being bitten a few times, he became so allergic that his face swelled up when handling shed skins. This sort of thing is apparently quite common among venom researchers also. Snake venom is just a thing that's pretty likely to give you allergies. I don't know if it's actually happened to a hognose keeper yet (most hoggies won't bite), but it's well within the realm of possibility.

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