that depends on your meaning of "pure." If you mean, can an animal be bred to become its own breed, then yes it can become pure. There are many varieties of "cross breeds" of dogs that eventually became recognized as their own breed (ie: "pure." ) The same has occured with cat breeds, livestock, etc. Some breeds involved crossing two or more known breeds, some involved crossing two or more species (check out Bengal cats, Chausies, Savanahs, etc., and there is a "pure breed" of dog that includes wolf in its direct lineage. Also, cows have been crossed with Buffalos to create a breed they refer to as "Beefalos." The list goes on and on.)

It is when an animal can consistently reproduce itself, and does not require further introductions from outside lines, that it becomes a "pure breed."

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