I was just going to reply to your thread lower down on the page (and move it up) when I realized that it was already moved up. Got a bit behind over the weekend with reading the forums.
Disclaimer....as always...I'm not a vet and I am only telling you things that I have seen/read about/heard of, etc. I hope that your vet can solve the problem for you. I feel for your poor chameleon...and for the worry that you are going through.
I have not seen many cases of swollen eyes....and only one that I can recall that remains unexplained.
One case was due to cancer. (The swelling was caused by cancer.)
In one case (WC dwarf jacksons) both eyes were swollen. I took her to the vet's and they tried to take fluid from the eyes, but none came out. They tested for bacteria and none turned up....so they did nothing. She died a few days later. An autopsy was done. Its stored away at the moment and I can't get to it....but I don't remember anything significant being in it to do with the eyes.
Another one (Meller's) came to me with an infection in the sinus area. They eyes were NOT swollen...there was a big bump below the eye. I took him to the vet's and surgery was done to clean out the sinus area. Because the infection went so close to the eye, the eye was swollen huge by late that same day. All this to say that something in the sinus area could cause the eye to swell...but I would expect it only to be on ONE eye.
Here's a site that talks about swollen/bulging eyes....
http://www.anapsid.org/eyebulge.html
Swollen/Distended Eyeball.
"In all reptiles, bilateral or unilateral swelling may be associated with an infection inside the eye itself, or behind the eye in or behind the socket; left untreated, it can lead to retinal detachment, blindness or enucleation (removal of the eyeball). Or, it may due to an increase in intraocular pressure, often a sign of infection, injury or some other health problem; left untreated, it can lead to retinal detachment and blindness. Since the cause cannot be determined by the herp keeper, nor are appropriate treatments available over-the-counter, these reptiles need to be seen by a reptile vet."
Here's one, but the eyes here contained blood in the swellings...however, the vet (Margaret a. Wissman, D.V.M. Diplomate, A.B.V.P.) does talk about swollen eyes being caused by a vitamin A deficiency...
http://www.animalnetwork.com/reptiles/detail.aspx?aid=25769&cid=3977&search=
contact information...
http://www.toolady.com/vetrefer/states/florida.htm
Now..for the vitamin A story....
Vitamin A can be preformed or from a beta carotene source. It is said that beta carotene can not be overdosed because it is changed into vitamin A in the body and only enough of it is changed for what is needed. Preformed can be overdosed since its already in a form that the body can use and any excess is stored in the body (liver, I believe) of the chameleon. Now then, just to make it as clear as mud...there is some question as to whether chameleons need preformed vitamin A.
Here is a site that talks about Hypovitaminosis A (too little), etc....
http://www.seavs.com/case_studies/lizards/
Scan down to hypofitaminosis A and read from there...
In turtles, too little vitamin A usually results in swollen eyes.
Here's a site about that...
http://www.anapsid.org/eyebulge.html
Hypovitaminosis A
"This is a disorder that primarily affects chelonians, specifically aquatic species. Fortunately, as proper diet and care information becomes more widespread, the incidence of hypovitaminosis A (deficiency in vitamin A) has decreased. However, hypovitaminosis A has become so associated with swollen eyes that too often turtle keepers (and some vets) just assume that swollen eye = A deficiency and promptly shove vitamin A into the reptile without doing anything to investigate the cause of the swelling. Since the health problems associated with hypervitaminosis A (overdose of vitamin A) are as bad in their own way as too little vitamin A, the poor turtle's pain and health problems are just made worse.
Early on, there is some swelling of the eyelid, some mild welling around the iris, and some tearing of the eye in cases of hypovitaminosis A. In addition, there are changes in the orbital glands. As the condition progresses untreated, the swellings become more pronounced and the conjunctiva becomes visible, swollen and reddened. Reptiles that depend upon sight to feed can no longer see well enough to feed, and so slow starvation sets in, further weakening the reptile.
Along with the necessary correction of the diet and environment, and the administration of vitamin A, the cellular changes in the cells of the eye predispose the already stressed reptile to infection, so the application of a suitable topical antibiotic ointment is recommended. During recovery, artificial tears may also be useful.
Ciprofloxacin and similar opthalmic drops have been recommended over gentamicin drops because of a reported epitheliotoxic (kills epithelial cells) effect of the latter."
Nekton Rep used to contain preformed vitamin A and it looks like it still does (retinol is preformed vitamin A)....
http://www.nekton.de/html/html_eng/n_info_rep.html
lele said..."I am the wrong person to ask. Kinyonga (and a few others)was helpful in explaining it all to me when Luna had some neck swelling"..thanks for the kind words lele...but I'm no expert.
pernads said..."Lele, is there a way if the vet can find out if his Vit. A levels are where they are supossed to be?? Can this be determined with bloodwork. Im taking him back on Friday for another checkup"...I know they can test for vitamin A...but I don't know if they know what the levels are supposed to be.
pernads said..."I have given him 3 treatments of the antibiotic, and I have noticed that his eyes are more round, they look a little shallower, and his eyes are a lot more alert. He has been very active today, and doesn't really mind when I put the antibiotics on his eye. He is a very freindly chameleon, unlike his lady friend"....I'm glad to hear that the eyes look a little better!
Wish I could be of more help. Hope that the problem gets solved! Please keep us posted!