I copied this posting from another forum. Thought is was interesting.
Below is a letter sent to me by Jon Coote, the inventor of T-Rex's Calci-Sand, after I questioned him at great length on its dangers at the Global Pet Expo last February. I don't agree with all his answers, but he defends his product well. You may find it interesting reading.
Please don't flame me for the post...to borrow a phrase, "the opinions expressed herein are not the responsibility of the producer or network." Or however they phrase it when they do impromptu cast interviews on DVDs. LOL
Hope this finds you all well, and staying cool!
Jo
----- Original Message -----
From: Jgcoote@aol.com
To: webmaster@rainforest-pets.com
Sent: Thursday, March 01, 2007 11:58 AM
Subject: Re: Calci-Sand impactions
Hi Jo,
Following our discussions at last week's Global pet trade show, the reason that T-Rex first introduced calcium sand to the reptile hobby was for two reasons.
First, unlike silica, it is actually digestible, though at the grade size we use it for a substrate, this digestion process is slow and can therefore be overwhelmed if the reptile deliberately ingests a lot of it. We use the exact same calcium in our insect dusting powder MicroStick and this fine grade is digested quickly. It has to do with smaller particle sizes presenting a much greater surface area for the stomach acids to work on and so dissolve it quickly.
The particle size that we use for our calcium sand is actually very carefully thought about. It needs to be fine enough to pass through the gut in small quantities and/or be digested, but large enough to support a reptile without it sinking too far into it. Think about yourself say trying to walk on a two foot layer of beans - you'd find it tough trying to walk across it because you would sink down into it, then consider how easy it would be to walk across a two foot layer of potatoes? It is all about particle size. Larger particle size makes a better substrate.
Secondly, unlike silica sand, calcium sand forms a paste with stomach contents rather than a concrete, as does silica sand. This impacted paste in the gut can be readily treated by a qualified vet with liquid parafin or an intestinal peristalsis modulator, such as metroclopramide, which is given orally. Impacted silica sand concrete does not respond to this treatment and so invariably has to be surgically removed.
The obvious reason why a Bearded Dragon or Leopard Gecko would eat its sand substrate to excess is because it is deficient in calcium and/or vitamin D3. The less obvious, but increasingly common reason is that protozoan parasites, such as coccidia and cryptosporidium, can cause extensive discomfort to a Dragon or Gecko by destroying the lining of its intestines. This discomfort seems to stimulate the Dragon or Gecko to ingest sand and other substrates to excess. It is rather like the Dragon or Gecko is trying to treat itself. Maybe a raw and sore intestine full of sand feels more comfortable to it than an empty one. Unfortunately, as we know, the Dragon or Gecko can do itself even more harm if it ingests a lot of any type of sand.
This is an increasing problem, and one hardly ever seen when we first introduced Calci-Sand over a decade ago, because coccidia is estimated to now be endemic in practically the whole captive bred Bearded Dragon population and cryptosporidium is endemic in the captive bred Leopard Gecko population. It does not usually become symptomatic until triggered by stress. This stress can be caused by many things but insufficient temperature is a particularly common one. Coccidia is usually easy to treat once it becomes symptomatic. Drugs such as BayCox 5% solution from Bayer (0.5cc/kg as a single dose), Trimethoprim, sulfonamides or sulfa drugs are used. One brand that is frequently used in the USA is called Albon.
I hope the above helps you to understand that it is not normal for a Dragon or Gecko to voluntarily eat its sand substrate to the extent that it fills its stomach with it. It is usually a symptom of some underlying disease or nutritional problem. So it is not the fault of the sand itself.
Best regards,
Jon Coote, Director of Research, T-Rex Products Inc.

