it is best not to handle dragons after their lights go out at night. It wakes them up and they won't get the sleep they need, will be stressed etc.
Short disturbances at night that is infrequent, is ok, but definitely not weekly or more.
As for how leopard geckos and bearded dragons compare...hard to say. Both are commonly kept pets and both tolerate handling well enough though bearded dragons tend to tolerate it much better than leopard geckos. Other than that, there are many differences between the two. Activity time, temperatures, cage sizes, life expectancy, husbandry requirements etc. It is like comparing apples and oranges really...they are both fruits, but both have their own pros and cons.
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PHLdyPayne