If it were me I'd tile the floor and also tile part of the walls as you often see if bathrooms. Basically a tile wainscoting like this:

I think this would add a lot of value to your home and be somewhat easy to clean. You should probably put down a moisture barrier between the walls/floor and the tile. Look into your local code for such work as what might work here may not work in your area.
For making the room escape proof, I'm pretty sure a typical room should be pretty close assuming it does not have attic access with a push up door or a drop ceiling.
Is there some area that you are particuarly worried about?
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Currently keeping:
6.10 Gonyosoma oxycephala (Javan, mixed colors)
1.1 Philodryas baroni
1.0 Rhodesian Ridgeback