Hi there!
In all honesty, it's not so much that "too large of an enclosure" will stress a Burmese python, but more so "the lack of good hides" and a few other things. It can be done, but not by everyone, and not without more of an effort than usually required. If you didn't already have the big cage I would, without a doubt, suggest a much smaller one.
Someone mentioned being in the wild, is the world too big for one(?). In essence, they're right - however, the problem with that is most people don't consider "everything" about their wild environment. The ones that wander into areas with little to no cover, or traveling the long distance between good hide locations, are taken out of existence by predators or climate elements. There is a reason they produce such large amounts of eggs.
OK, sorry for kinda driftin' off there - Personally, I'd block off at least half of that 8ft cage or start it out in a tub or something else smaller.
Here are some things to consider:
1) A hatchling doesn't "need" near that amount of space.
2) You'll be heating/maintaining a lot of extra space.
But with some understanding of what they need & desire, along with some craftiness, you can pull it off.
Best wishes!
HH
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Due to political correctness run amuck,
this ol' hillbilly is now referred to as an:
Appalachian American

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