Find the weight of water and figure out how much weight 50 gallons is. I'd help but I'm lazy and don't remember if there are 1.49 lbs. of water per liter, gallon, something else, or even if the number 1.49 is remotely accurate at all.
Anyway, remember two things. One, that the weight wouldn't be evenly distributed, and then, two, that the weight would also be placed upon parts of the glass that aren't that sensitive (the bottom of the tank is usually smaller than the sides).
I know it's not much help but I hope at least it will get you going. Good luck and let us know what you figure out.. I know there are a few articles about it on the web, but I just broke a tank the other day, just with water, so I wouldn't push it.
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