When Bandit first started having seizures, at about age 2, he had maybe 2 per year, always coinciding with the blowing of his coat in the spring and fall. The vet did not want to put him on medication because of his age. She said that the meds are hard on a dog's liver and since he'd have to take them for life, she didn't want to start him on meds any sooner than she had to. Back in 2006, I tried him out on KBr (potassium bromide). The side effects were just disastrous for Bandit: extreme thirst, extreme hunger, ataxia. The hunger was the worst. Not only did he gain about 20 pounds in 3 months, despite my efforts to supplement his food with low-calorie fruits and veggies, but his hunger altered his behavior. He began counter-surfing and getting into the trashcan and chewing random stuff up around the house. Also, his temperament changed and he became more unpredictable -- edgy, snappish, difiant. I couldn't trust him around other dogs. The KBr was $48 per month, could only be purchased from one compounding pharmacy (that was no where close to my house, and which kept hours like M-F, 10-4). I was probably spending an addition $30 per month on fruits and veggies, on top of his $25 per month kibble. And then he had to have a blood check-up every three months, to the tune of $150. All of that, and the medication wasn't controlling his seizures. So we took him off the KBr. Within a couple months, all his side effects went away, he lost the weight, and went back to being his usual cooperative, good-natured self.
I just started him on phenobarbitol. My vet had been really resistent to the phenobarb because while Bandit's blood tests always come out normal, an x-ray from a couple years ago revealed that he has an abnormally small liver. Since phenobarb is hard on the liver...well, she was concerned. But I don't feel like we have much choice. Bandit's seizures are more frequent. He had 3 in November (including 2 grand mals), 0 in December, and so far 3 already in January. Mostly he has petite mals -- that's what I call them; they're not the full-body convulsions that are the grand mals, and he's much more conscious and aware during the PM seizures -- but they just occur too frequently. And I'm spooked these days because Bandit's brother Bodie (who belonged to my brother) died from his seizures back in October. He went into status epilepticus and his body temperature went up to 116. The vets euthanized him.
Anyway, so far Ban's doing okay on the phenobarb. He's very thirsty and I'd say his hunger has increased as well, although I haven't increased his food allotment. He's also incredibly wobbly on his pins, poor guy. He moves like a drunken sailor. I think he feels weird because he's crying a lot. He gets in bed with me, puts his head on my stomach, and just whines. But the vet told me all this should pass in a couple weeks. I hope so.
Oddly enough, my family always has epileptic dogs. Of the 10 dogs we've had in the last 30 years -- 2 Shelties, one lab mix, and 7 Siberians -- 6 of them (2 Shelties and 4 Siberians) have been epileptic. The vets always told us it was a "pure-breed" thing. I've only just learned that it's more prevalent in Sibes than in a lot of other breeds. (Our 4 Sibes who have the epilepsy are all related: Mama and her 3 puppies. Mama passed on the gene.)