Hi Kristen,
Toe swelling can occur with almost any species of reptile. It is an infection - most likely some irritation around the toenail and it has closed up - causing the swelling due to internal infection.
First, let me say that this can get serious if not treated. Our vet showed us pictures of an iguana that had this problem - and with neglect, it developed into gangrene - and he had to remove the leg just below the knee to save the animal's life.
The treatment is foot-soaks: very warm water deep enough to cover the foot. We add a tiny bit of antibacterial soap to the soak. If he doesn't mind wading in a tub, that method is good. If not, you can hold a cup of water and dangle that leg into the cup while you are holding him. The soaking should be for a min of 15 minutes, twice per day.
Then we further disinfect the area with Betadine. If you don't have that, use hydrogen peroxide (warmed).
Squeeze the toe with steady pressure toward the toenail. You may see a greenish, cloudy fluid come out around his nail - this is good! You want to get that out - as it is the stuff causing the swelling. Don't squeeze so hard that you hurt his foot, - but try to get some of the fluid out. Once you do, disinfect again. If you don't, more soaking is necessary.
If you cannot get the fluid to exit, a vet might have to lance the spot and squeeze it for you. Most likely the vet will prescribe Baytril to be administered orally. This helps the infection from spreading further.
With some chams, we have been successful in arresting he infection with the soaks and squeezing, disinfecting the area and applying a triple antibiotic ointment (or SSD cream). With a few, we started on the Baytril if it looked as though it was going to be stubborn.
Don't wait too long... and keep us posted.
-----
