Brian,
My Swiss Websters are all set up in colonies of 1.5. I have them all on automatic water and feed them 50% lab blocks and 50% my own grain mix I described in a post below. They are all in rack type systems.
The mouse room is a two car garage. It's insulated and air conditioned in the summer, our winters here are very mild so I don't need heat. I try to keep the temperature between 70 and 75* year around. I have a light that is on a timer to give me about 12 hours of light and I leave it at that year around.
I have enough tubs that I can replace their tubs with a new one every Saturday, then I dump the old one and wash it with hot soap and water. (Which is what I am about to do this morning).
I have quite a few snakes and they are eating mice and rats of all different sizes so at any given time I need mice and rats of all sizes. As I go through the colonies, if one colony seems to have too many fuzzies, I pull half of them. If two females both have a litter of 15 at the same time, I know it's going to get too crowded when those get bigger so I pull half of them. I think you can loose lots of babies just because they are too crowded.
When the mice get to weanling size, I kill as many weanlings as I need, set aside as many as I want to grow to adults, and sell the rest to pet stores. I am selling about 600 weanlings to the pet shops per week. I also sell about 300 frozen pinkies a week.
I keep good records of the colonies. I record everything I take out of a colony and then average it every 4 weeks. I call it a mouse unit weather it's a pinky or weanling. Each colony is expected to produce and average of 10 mouse units per week. Most are producing 15-20 per week. If their production drops to 10 or below, I pull the male. Three weeks later, I know that none of the females are pregnant and I pull them as jumbos.
When I need to increase the number of colonies I'm keeping, I look at the records and pull future breeders only from the colonies that are producing well. I think this is the most important part. Over the years, I have doubled my production with the same number of colonies. I think it is because I have selected only good mothers that produce good milk and good fathers that are fertile and attentive to the girls.
Hope that helps.
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Wade's Weptiles & Wodents