I'm not going to claim to be an expert, but I do have some bp experience and have seen a number of posts of yours, and I'm going to hazard a guess that your bp doesn't feel secure.
If you want to test this and possibly cure the behavior, set up a new cage that's 1/5 or 1/4 the size of the one he's in now and has two or more solid, snug hides (flower pots, pvc pipes, etc., as long as it's snug, dark, and has some weight to it). Of course the temps and humidity need to be right and he needs either no light or a proper photo period as well.
Leave him in the new setup for a month (taking out to feed and occasionally handle) and make sure that when you approach him to pick him up he can see you coming before you touch him and that you go toward his body instead of his head.
If there is no change to his behavior in a month, then it may not be a security issue, but I bet it is.
>>can someone please tell me why is my Oz so f%/#"*g agressive?
>>everytime a try to take him out of his cage he puts his body into S position...he also tried to bite me (already 3 times and my friend once!)
>>i don't know why!i first thought it was because he was hungry, but i fed him with 3 mice,, wait 2 days and then try to hold him,,,but here we go again, defensive position!!
>>any advise?
>>-----
>>1.0.0 Ball python (Oz)
>>0.0.1 Hardwicki Uro (Amon)
>>0.1.0 Black cat (Tomika)