I think in part what makes cham's high maintenance is hydration. You have to be sure that it drinks every day and that you keep the humidity up in its cage (not tank unless very young). You also can’t throw in a bunch of crickets and a water bowl and go on vacation for a week. If you go away frequently, you will need to have a reliable, trusted friend to care for it. My suggestion to you is to go to the sites I have listed below and spend some time there looking around. Don't just go to the home page but look at articles, vet topics, etc.
But you might want to begin with this one:
www.chameleonnews.com/year2003/july2003/costs/costs.html
You also need to find yourself a vet within a reasonable distance from where you live - not a cat/dog vet but one that knows herps and their needs. Go here for a state listing then call one to make sure that the herp vet is still there. www.anapsid.org/vets/index.html
After you have done your research, come back here to ask questions. You would be better off researching WHERE you will get your chameleon – a pet shop is not always the best place.
ALL of these have info on breeding, husbandry, baby/nursery info, nutrition, species, feeders, health, vets and MUCH more:
Chameleon News
This is a top source of current information compiled and written by “tops in their field.”
www.chameleonnews.com/
AdCham
www.adcham.com/
Chameleon Paradise – a site by one of our forum posters. He has FAQ, do’s and don’ts, cage building
http://www.chameleonparadise.com/
Chameleon Journals – www.chameleonjournals.com/
Reptayls – another site by a fellow KS poster
groups.msn.com/REPTAYLSChameleons
Of course, there are more but these are the most frequently recommended. PLEASE go to them, look around and then come back to ask questions. Hope this helps you out!
lele
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0.1 veiled - Luna
0.2 house geckos - Gaia & Tia (MIA 
0.2 felines - Kyndra and Líta