Sorry for all the questions, but not being able to see the whole dragon or history, makes hard to access some other things.
Do you have other pictures of him prior to the lesions showing, like any just before? Also any "now" pictures of his mouth area?
Is he in with any other dragons and also can you tell me his light sets up? type, location, how close he can get to them.
Has he ween eating normally the past week? Has he been treated for anything internally within the past 6 months>
Do you know what nolvasan is? Its a cleaning agent that is often used to debrief wounds, fungi and bacterial infections in animals, it can be used directly on a sore or lesion and is also safe on them. Its also used to clean and rinse internal sores such as those found in the mouth.
Did you know that if you culture the skin of a healthy normal lizard, you have over 60% of chances to grow an Aspergillus or a Penicillium fungus? They are there on them, as a natural part of their dermis, and normally not a problem. Some things can set a colony of them off growing and many can exist under the scales and not be noticable until they have eaten through the dermis and create a scale loss.
You can try a scrapping culture and see if anything growns, but many of them are only detected in a tissue culture and another problem with scrappings is you may grown one that is there normally and not a problem.
I asked the above questions to rule out some other things and when you answer those we can go from there. If it is what I think it is, you are going to have more show up. If you use the nolvasan, it is also going to expose more spots like this, it is not making them, only exposing what is already there.
I not not know what to say about the antibiotics, from what you say it seems to be helping him which could make sense as the areas are probably septic now, but the antibiotics could cause the underlying problem that started this to accelerate and that is what I am concerned about. Reptiles do not have much tissue between the skin and the muscles, therefore it is relatively easy for a fungi to move through the skin to deeper tissues causing infection. But if that is the cause, you need to address that and the antibiotics tend to contribute to the problem in the long run.
I would do come cleaning and debriefing with the Nolvasan and see what happens, if it is what I suspect, it will expose more areas. If it is not that, it will not hurt the dragon and help clean the wounds of bacteria. Let me know the answers above and if you clean and debrief with the Nolvasan, let me know what happens.
Nolvasan can be found in most cattle, feed and seed, stockyard and farm stores.
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