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FENBENDAZOL(PANACURE)DOSAGE QUESTION.......

biggworm Oct 10, 2004 12:05 PM

I was wondering what the conversion of ml to cc where? Right now I have c.c syringes.My book says ml.The book says 2.27 ml per 10 pound snake.Your comments will be appreciated.Thank You. Ashley Lopez

Replies (22)

Biophiliacs Oct 10, 2004 12:32 PM

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biggworm Oct 10, 2004 12:50 PM

100 mg/g.The book(what's wrong wth my snake)says ,concentration 100 mg/ml. 2.27 ml per 10 lbs.So I should do 2.27 cc per 10 pounds.Is that right?Thanks for replying.

royerreptiles Oct 10, 2004 03:31 PM

Are you using paste dewormer? If so, than use 2.27 grams of the paste. The important thing is that you dose at 227 mg per 10 pounds.

>>100 mg/g.The book(what's wrong wth my snake)says ,concentration 100 mg/ml. 2.27 ml per 10 lbs.So I should do 2.27 cc per 10 pounds.Is that right?Thanks for replying.

biggworm Oct 10, 2004 03:43 PM

at at 100 mg/g of CONCENTRATED PASTE how many c.c does that convert to with a 10 lb snake? thanks for replying.

Biophiliacs Oct 10, 2004 04:51 PM

The dose would depend a lot on how many grams of paste are in one ml. Does it give that on the package?
Matt

biggworm Oct 10, 2004 06:21 PM

Equine Dewormer 25 gram Paste 10%(100 mg/g) I only have c.c syringes.So that's why I'm having a hell of a time.Thanks for your time to help me.

Biophiliacs Oct 10, 2004 06:40 PM

If its a 10% solution, pretty sure that'd be 100mg/ml. But if that tube is 25 grams total, then it might be different. The problem is that mg(weight) and ml(volume) aren't interchangeable. Otherwise it'd be around .3 cc per lbs. Sounds like a lot, but retpiles get 10x's the dose that a mammal would. I'm going to check up on this and I'll get an answer to you tomorrow.
Sorry I couldn't be more help-
Matt

royerreptiles Oct 10, 2004 06:40 PM

>>Equine Dewormer 25 gram Paste 10%(100 mg/g) I only have c.c syringes.So that's why I'm having a hell of a time.Thanks for your time to help me.

royerreptiles Oct 10, 2004 06:42 PM

It certainly would have been easier to dose liquid, and it would have been a better choice to use ivermectin (my opinion).

The point is, you don't need to know mL...you need to weigh the paste on a gram scale and then dilute the needed amount with water and dose the snake. Pretty simple.

Biophiliacs Oct 10, 2004 07:00 PM

Then it'd go like this...
Concentration; 100mg/g
Dosage; 75 mg/kg
Conversion; 2.2 lbs/kg
Weight of animal(in pounds); W

(1g/100mg) multiplied by (75 mg/kg) divided by (2.2 lbs/kg);
Gives you dosage per pound of 0.3 grams per lbs;
Then multiply 0.3 g per lbs by W(pound of boa) and you get the total dose.

Seems like a lot, maybe not..

royerreptiles Oct 10, 2004 07:56 PM

close, but there are 1000 milligrams in a gram, not 100...so the dose would be .03 grams per pound (or .3 grams per 10 pounds)

>>Then it'd go like this...
>>Concentration; 100mg/g
>>Dosage; 75 mg/kg
>>Conversion; 2.2 lbs/kg
>>Weight of animal(in pounds); W
>>
>>1g/100mg) multiplied by (75 mg/kg) divided by (2.2 lbs/kg);
>>Gives you dosage per pound of 0.3 grams per lbs;
>>Then multiply 0.3 g per lbs by W(pound of boa) and you get the total dose.
>>
>>Seems like a lot, maybe not..

biggworm Oct 10, 2004 10:08 PM

N/P

Kelly_Haller Oct 11, 2004 12:03 PM

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royerreptiles Oct 11, 2004 02:37 PM

How do you figure?

the dosage she inquired about was 2.27mL per 10lbs of 100mg/ml solution
multiplying 100 x 2.27, you see you need 227mg of product to treat a 10lb snake
Dividing by ten, you find you need 27.7mg per pound. That converts to .0277 grams PER POUND. Round that up (still in the safe effective range) to .03 grams per pound.

.3 grams per pound would be ten times the dose.

www.onlineconversion.com

Kelly_Haller Oct 11, 2004 09:30 PM

Fenbendazole is dosed at anywhere from 25 to 75 mg/kg of snake body weight. The dosage from her book of 2.27 ml of a 100mg/ml solution for a 10 lb snake is the same as 22.7 mg/lb, which equates to 50 mg/kg, which is a mid-range dose. This is the .0227 g/lb which you rounded to .03g/lb, and is correct for the give solution.
In her second post, she stated that she had a paste that was at a conc. of 100mg/g. A 0.3 g/lb dose at this conc. equals .03 g/lb and is the same dose as what you got above for the liquid. The paste is at only 10% fenbendazole and so requires 10 times the weight to give the equivalent weight dose.

Kelly

biggworm Oct 11, 2004 10:06 PM

Should I get a syringe that shoots grams or can you pls tell me how many c.c of PANACURE at 100 mg/g (10 % consentrated PASTE)for a 10 pound boa.Oh teah,Linda I'm a HE not a SHE.I get that all the time cause my name is ASHLEY.I was born on ASH WEDNESDAY.go figure.So 1ML = 1.0 c.c or .10 c.c thanks again.

royerreptiles Oct 12, 2004 01:58 AM

Sorry about the gender confusions...

You can't use a syringe to pull your dose. Syringes measure volume, not mass. Although you can draw this paste into a syringe, even if it worked out by some miracle that 1mL of paste contained exactly 100mg of Fendbendazole you can't draw the paste like you can a liquid. There are inevitably air spaces in the syringe when you pull a paste. In a liquid, you can "tap out" the air bubbles...something that you just can't do with the paste.

Using a liquid would be far preferable to this method, but you can work with it. As Kelly stated, the dose you are working with is mid range, so even if your snake does not "get it all" (as long as it gets most of it), it will do the trick. Depending on why you are deworming this snake, you may want to repeat treatment in a few weeks.

Get a gram scale and put a small piece of paper on it
Zero the scale
Squeeze out roughly 3 grams of the paste (this contains 300mg of Fenbendazole) This quantity of paste is sufficient to deworm a TEN pound snake

Now, there's three "delivery methods" that would ensure your snake gets the entire dose where it needs to be.

The first would be to stick the paste in a dead rat and feed it to the snake.

The other method would be to tube the snake orally (feeding tube) and dispense the medication that way. This off course, requires that you know how to tube a snake and you would also have to mix the paste with water so it would be of a consistency conducive to being passed through a small tube. Add that this paste doesn't mix so well with water and this method becomes even more inconvenient.

The third method would be to draw your measured amount of paste into a syringe and simply place the medication in the back of the snake's mouth (like you would for a horse) Unfortunately, there is no guarantee that the snake actually ingests it.

You could save yourself alot of headache by using Ivermectin, which is a very effective broad spectrum dewormer. You would absolutely *HAVE* to make sure you dosed it correctly though. In the pig and sheep formulas of IVOMEC that you can get at feed stores both translate into a very small liquid dose for the snake, which is effective given both orally "back of the mouth" and by injection. That's a whole new can of worms.

>>Should I get a syringe that shoots grams or can you pls tell me how many c.c of PANACURE at 100 mg/g (10 % consentrated PASTE)for a 10 pound boa.Oh teah,Linda I'm a HE not a SHE.I get that all the time cause my name is ASHLEY.I was born on ASH WEDNESDAY.go figure.So 1ML = 1.0 c.c or .10 c.c thanks again.

royerreptiles Oct 12, 2004 01:29 AM

OK we were just talking about two different things. I was still trying to make the point that regardless of the medium, she still needed roughly 30mg per lb of Fenbendazole. I was trying to illustrate that you need to focus on the weight of the drug, not the whole compound and got caught up in my own argument.

For the 10% horse dewormer paste
.11 grams to .35 grams per pound of snake.

Consequently, for a liquid suspension of 100mg/mL, the dose would be the same-just remove "gram" above and replace it with mL
Cool

>>Fenbendazole is dosed at anywhere from 25 to 75 mg/kg of snake body weight. The dosage from her book of 2.27 ml of a 100mg/ml solution for a 10 lb snake is the same as 22.7 mg/lb, which equates to 50 mg/kg, which is a mid-range dose. This is the .0227 g/lb which you rounded to .03g/lb, and is correct for the give solution.
>>In her second post, she stated that she had a paste that was at a conc. of 100mg/g. A 0.3 g/lb dose at this conc. equals .03 g/lb and is the same dose as what you got above for the liquid. The paste is at only 10% fenbendazole and so requires 10 times the weight to give the equivalent weight dose.
>>
>>Kelly

bahreptiles Oct 10, 2004 12:37 PM

I pulled out my syringes and it looks like we are talking .15cc to equal your 2.27ml. It is 16ml = 1 cc. hope this helps. You can do a search on yahoo for conversion charts as well.
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Voices in the darkness... scream away my mental health. Can I.. ask a question.. to help save me from myself? Enemies fill up the pages, are they me?... Monday till Sunday in stages, set me free!!! " Diary of a Madman " Ozzy Osbourne

biggworm Oct 10, 2004 01:28 PM

THANK YOU!GOT IT! N/P

royerreptiles Oct 10, 2004 06:46 PM

Sorry, this is very wrong. one cubic centimeter (cc) is equal to one milliliter (mL). This kind of misinformation could lead to a toxic overdose. If you don't know what you are doing, please do not medicate your snakes without talking to a vet.

>>I pulled out my syringes and it looks like we are talking .15cc to equal your 2.27ml. It is 16ml = 1 cc. hope this helps. You can do a search on yahoo for conversion charts as well.
>>-----
>>Voices in the darkness... scream away my mental health. Can I.. ask a question.. to help save me from myself? Enemies fill up the pages, are they me?... Monday till Sunday in stages, set me free!!! " Diary of a Madman " Ozzy Osbourne

Kelly_Haller Oct 11, 2004 11:39 AM

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