Russ,
our group of sonorans is fairly small. ( 3 males and 7 females) When we started with them again 7 years ago we out bred the color morphs to normal wild caught animals from the center of the range in order to reduce the possibility of birth defects, reduced viability of the eggs and neonates etc. So far we have not experienced any problems from these hets and the subsequent albinos etc. that have been produced. But we watch the lineage of individual animals and the results very carefully each year to get desired results.
In the original animals I was working with we had produced 11 clutches over three years and had some end of tail kinking and some other problems such as reduced colors etc. Relatively a very small portion of the hatchlings had any problem at all. Of the 11 clutches a total of 91 hatchlings were produced and we had a total of 3 that had the tail problem and we had 4 that never fed. Since we started the het production and susequent production of albino's etc. we have produced a total of 147 hatchlings (hets, albino's and hypo.) with all feeding and no visible problems. Additionally the viable egg production is running about 97.53 per cent.
I attributed the original probelms to in-breeding in the original lines and just a general lack of genetic diversity in our lines. That is probally a reach on my part, but I am somewhat anal about this from past experience with other colubrids that originated from single or very small groups of morphs. (for instance albino ruthveni males having severe sperm viability problems, leucistic Texas Rats with bulbous eyes etc.) It should be noted that the problems have cleared up since then with the out breeding. We did this several years ago with Leucistic Tx. Rats to reduce the bulbous eyes and it also cleared up. It is a long process of breeding the normals to the albino's, anthy etc and then recreating all the subsequent morphs from hets, but we feel it is worth it over the long haul.
One of the side effects or results from this type program is you can pick the attributes of the various hets that are used to produced a certain look in the color morphs that you personally like. It is pretty apparent that when breeding the hets the darkest and sometimes ugliest of the normal looking hets produce the prettiest of the albino's etc. The darker colors produce a great deal of contrast and brighter reds when displayed in an albino animal for instance.
This is just our approach though and I have several friends that are working with sonorans and are having no problems with the lines that are on the market at this present time.
Bottom line my suggestion is to use your best judgement and evaluate your animals on an individual basis and go forward with what feels right for you.
Anyway good luck with the project, you will enjoy them no matter what you decide to do they are really great animals.
John Cherry
Cherryville Farms

Cherryville Farms - Reptiles