The vipers are all still in the family Viperidae but there are two subfamilies, Viperinae and Crotalinae. The rattlesnakes (and other pit-vipers) are in Crotalinae, the non-pit containing vipers are in Viperinae (although Azemiops actually resides at the base of the pit-viper tree despite not having pits).
The distinctions between these two lineages is infinitesimal compared to the vast differences between 'colubrid' families such as Colubrinae (e.g. Boiga, Elaphe), Homalopsinae (e.g. Cerberus, Enhydris), Natricinae (e.g. Natrix, Rhabodophis), Psammophiinae (e.g. Malpolon, Psammophis), Pseudoxyrhophiinae (e.g. Leioheterodon, Madagascarophis), Xenodontinae (e.g. Heterodon, Hydrodynastes). Some of these families (e.g.. Psammophiinae, Pseudoxyrhophiinae) are much much closer to elapids than they are to other 'colubrids'
Cheers
BGF
Venom & Toxin Database