The more unrelated the pair the stronger their genepool will be. There are known boa deformities that have been hypothesized to of been caused from excessive inbreeding. I personally believe deformaties we see in albinos are moreso from excessive inbreeding vs the supposed weakening of the mutation itself (amelanism, a.k.a. albinism). We would see more inbreeding from a recessive line vs a polygenic or codominant line. The majority of het albinos that are sold are probably sibling pairs (just a guess). The bang for buck for the pair deal is too cash effecient to pass up for many, considering its a recessive trait and they need a het (or homozygous for that matter) mate anyway.
Crosses are geneticly superior to all pure-breds. Same concept as whats known as "hybrid vigour". Hybrid animals are always more hardy and overall healthier with less mutations and deformaties versus purebreds.
Bottom line: By inbreeding you undoubtably weaken the genepool to at least some degree (what degree is debatable). The only time I would reccomend inbreeding it is to extract or prove out a particular trait.