i agree with the others- try just sitting quietly by his tank a lot, and just resting your hand in there. i find it's a good idea to handle them (whether they like it or not) once every two weeks, just because (in my personal experience) they tend to get terrified if you haven't ever handled them, and then you have to take them to the vet, or take them out for removing stuck toe sheds. i do have one adult male that has never calmed down, and who is extremely agressive (his name is rasputin). and what i do (as he needs to be handled fairly often, as he's not good about removing toe sheds), is just use a paper towel to pick him up. thin enough to get a good hold (and not hold too tight), but thick enough to keep a bite from hurting. and even when he does land one, it really doens't hurt too bad, other than my ego. and i've found that, with time, as he feels i'm removing his toe sheds and not hurting him, even rasputin is trying to bite less often.
another technique i use on my most nervous ones is to put little pieces of fabric i've been wearing around, in my clothes, into one of their hides (no perfume or anti-perspirant, though). then they get used to my smell a bit. can't tell if it helps, but rasputin seems to like the fabric either way. 
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marla
currently: 0.0.9 catfish, 0.1 ferrets, 2.8.3 leopard geckoes, 0.0.13 oriental fire-bellied toads, and 0.2.0 sugar gliders