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Hybrid genetics

justin stricklin Feb 21, 2005 09:42 AM

Alright, this may be confusing but bar with me...
Ok, lets say I get an albino banded water snake. I breed it to a normal midland water snake.. Shouldn't that make the babies het for albino? then I breed the siblings of hets together... then I breed the offspring of the hets which should be albino to a normal midland water snake. Make some more hets and then breed those siblings together shouldn't that make a pure albino midland water snake? because I thought that if you have like 50% of the snake as midland and the other 50% banded then the continuel breediing of it to midlands should make it pure shouldn't it? It sure woudl be a long process, but I am realy into water snakes and I just know they will be a popular snake after a few years of a few people captive breeding them. They are easier to keep than just about anythign and have so much more of a personality. Well, if anyone could let me know about that question I would be greatly pleased, I just do not know if that is how it works.
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Justin

Replies (5)

ZFelicien Feb 21, 2005 01:38 PM

I'm no waters snake fan so I have no clue that the snakes in question look like but ... if you were to try what you stated the snakes may look very similar to the midland water snake, but they will NEVER be pure ... genetics may be rather close but I very much doubt it'll be pure.
but if you're looking for the appearance then what you propose should yield an albino snake that's similar in appearance to the Midland water snake

~ZF

Bigfoot Feb 21, 2005 07:45 PM

What you would be doing would be introgressing genes from the banded species into a midland genetic background. You would wind up with a domestic snake that would look like an albino midland but would not be a pure midland. I don't know what the advantage that would be over an albino banded, especially since it would likely drive the purists nuts. Perhaps you can explain.

Doc

justin stricklin Feb 21, 2005 08:19 PM

Ok thanks. That was pretty much an example I gave you. If I were to do that I would go do it with a banded to a yellow bellied water snake. They look much diffent but are very similar. I am sure as long as I told the people Iw ere sellign them to before they buy then I should not have problems. However, I am not in this business to make money but I do like it to pay for its self and possibly more. These species integrade in the wild where their ranges meet anyways. But still, if you've seen albino waters then you know just how good they look. they look better than any corns I've seen. Much brighter and just so beutiful. If i do that I will be sure to do it with something that will look better with the colors and pattern of a hybrid. Most likely I will not breed hets or albino bandeds to yellow belly or midlands, but somehtign like diamond back water snakes. They have a very good pettern and I could not imagine what it would look like with an albino. but if I can get some hets or albinos of the desired species I want, I will do that instead. As long as they are not realeased into the wild. Before I sell an animal I always make sure the buyer is responsible and has a real interest in them, and nt in it just for money.
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Justin

bluerosy Feb 21, 2005 08:13 PM

I asked this similar question about a week ago on this thread.

http://forums.kingsnake.com/view.php?id=708724,708724

Posted by Kingmilk feb 7,'05:
I did mention something to that effect, but I don't think my original point was ever understood. What I intended to express was that the level of testing that was available two years ago, and three years before that time when I was looking at haplotypes in Gallus domestics, could not have revealed more subtle differences. There may in time be techniques that could really reveal on a molecular level, a hybrid event, for many many generations to come. At this time, we are nowhere near that. Thus, "masking" genetic differences can be accomplished through "backbreeding", which is taking the hybrid f1 back to one of the parent forms and then going in that direction for generations. In some of our very simple tests, for instance MtDNA, this factor can be manipulated in this manner. For instance, if you take your male f1 hybrid and breed it back to the female of the species whose MtDNA you want represented, you will then pick up that MtDNA and all that generation will show the MtDNA of the special form in question. This does not mean that this animal is then "pure", but that on the MtDNA level, it would be indistinguishable from "pure" forms of the MtDNA line. For instance, in laymans terms, if I choose to make a jungle corn and I breed a male cal to a female corn, I get f1 hybrid, junglecorn which has MtDNA of corn, but is 50% genetic material from each parent. If I want my MtDNA to say "cal", then you take the f1 jungle (corn MtDNA) back to a female cal and all those offspring show "cal MtDNA". This always works this way and shows the limits of MtDNA as a major marker factor in genetic work. It is in the nuclear DNA that the real story is happening. Except for the sex-linked genes at the X and Y chromosomes, all these genes are based on the many, many alleles on the chromosomes. You get one half of your total package from each parent, so the first thing to consider is that closely related lifeforms (and these snakes which can produce fertile offspring definately are closely related) may share almost all of their genetic material in common. We share 98% with chimpanzees, so imagine how much closer it is in say ratsnakes and cornsnakes or the various forms of getula. Thus you really dont have that many variable alleles. The variations at thsoe alleles may be great, especially depending upon the distance in time from species split behind the two forms, but those which can produce complete fertility in their f1 offspring are not very differentiated , thus probably not very far apart in time, as their seperate evolution goes. Thus you would require a complete gene map of each parent species (as has just recently been finished in humans and poultry, at considerable expenses)to look for any variations in the genome. This would then be your markers. It is by looking for markers that genetic difference is notated. Back breeding and selection can allow you to go back to complete genetic "purity" (i.e., a complete match to the original genome of either parent form) by using molecular markers in each generation to narrow and weed out the genes remaining from the alternate parent forms. However, this would require access to a full mapping of both original species and the ability to map the offspring for comparisonin each generation. At our current level of knowledge we could accomplish this. However, applying it to our hobby animals is unlikely, as this is an very costly process.
Using the simple markers that are generally used at this time in all animal registries and "DNA fingerprinting", outcrosses can vanish from the record, even on a molecular level relatively quickly, as per the testimony of those given tests. If selection toward the visual phenotype of the desired type is made, you will end up with an animal which is visually indistinguishable from the pure species, and it is even possible to mask the hybrid origin on gene tests as well, if you know how to get around a certain test, such as the MtDNA test, and you are dealing witht he simple tests which are more available at this time.
Finally, I think this information is actually counter-intuitive to what I wish to see happen. I think conservation of pure forms is fantastic. I just personally have no interest in it what so ever. What I think the hybrid community needs to be focusing on is moving forward with true domestic strains, that have nothing to do with "wild types" (which should be part of conservation). The hybrid strains, which in time will be simply "domestic colubrids" or something such, can compliment the moprph forms of pures in the hobby and pet trade, and can allow the complete closing down of wild catching, which it is simply beyond belief that this is allowed to continue, when so many wonderful things are happening with captive breeding, both through morphs on "pures" and with hybrid strain development. One thing my research has shown me is that all the best stories and all the best data can never confirm beyond a shadow of a doubt that something is "totally pure", but I think it gives one pause to consider the rapid emergence of so many morphs so suddenly in captive breeding.
I hope this answers your questions Rainer. Thanks.
BR

justin stricklin Feb 21, 2005 09:32 PM

I think that wa one of the best responses I have ever had on any forum. I had to read it a few times but I get it. I agree about people need to stop removing reptiles from their habitat. A few W/c is alright to broaden the gene pool. And some need to be caught in the begining to start captive breeding. That is what I mosly do with water snakes that I can catch in my area. They are so common and there is no one breeding them. I am sure after people realize what a great species they are to work with they will give them a shot and they will most likely enjoy them. I agree with you totally. But I think we do need to keep around the wild caught looking specimens. You know, bred to nothing special just a regular type that you might see in th wild. for example retics to me are most beutiful in their normal color. Most water snakes are absolutly magnificant looking too.
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Justin

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