I have a female okeetee, Arrow, who I've had for about 4 years, and who is about 49". She's usually a real pig (We sometimes joke about how, if given the chance, she'd keep eating mice until the first one came out her butt, haha) and very very eager to eat (she's eaten 5 adult mice at one time) but about a week ago, we bought her two adult mice, and she ate the first one.. but then, with the second one, she would spit it out and then try to swallow it again, then spit it out. I ended up taking the mouse from her and washing it off, then giving it to my ball python (who ate it). She wasn't thirsty, either, I moved her so that her head was over the water bowl, and she didn't drink. I have no idea why she behaved this way.
So, yesterday I tried feeding her a mouse and she was totally uninterested. She completely ignored it! She's also been really, really active lately. She became active before this feeding stuff happened.. a couple of weeks, maybe? She's showing the exact same kind of behaviour as my baby Western Hognose did last year (In the case of my Hognose, she didn't eat for about 3 1/2 months, and then started eating normally again.) When my hognose did that, we assumed it was related to hibernation or something because it was winter.. but it's the middle of may and I live in the California Bay Area, we get very mild weather here, and plus, Arrow lives upstairs in my bedroom - I like to keep the tempurature upstairs at about 85 degrees. ^_^'
Could this have any relation at all to the fact that I bought her a bigger cage recently? I wouldn't think so, because she had already eaten a couple of meals in that cage before this happened. (Cause I bought her new cage afew weeks ago.)
In case this information could be related, I always pre-kill mice before giving it to my snakes, because they're both so dumb - they'll bite the mouse on the butt. Arrow used to have afew scars because of that. I kill the mice by either crushing the skull or snapping the neck or spine, so they twitch and kick, but can't bite. I've been doing this for a couple years now and it seems to be the best feeding method.
Sorry for writing this novel of a post, but Arrow was my first snake, and is my favorite snake in the world. Better safe than sorry!
By the way, here is Arrow in her old cage. She's my baby 
That is carefresh substrate in her water bowl btw, not poop.
