Well, I'm not qualified to answer the question in your header, but snakes definitely recognize and respond to differences in handling- for example kids tend to be much more frenetic and the snakes react by not settling down.
What level of recognition they have for individuals might be debated a lot- I think their excellent sense of smell/taste and repeated exposures to their main handler would lead them to be aware if that person is handling them or a stranger.
I try hard to not anthropomorphize my animals, understanding the animal's point of view is key to successful training and general care.
I think snakes really only respond to cues having to do with survival, ie environmental conditions (heat/cold), food cues, mating/competition cues, and fear of harm. Whether some snakes see handling as a welcome and stimulating change of pace, or all just see it as a stress, is much argued.
They definitely have very individual personalities!