Here are some notes to your questions from my perspective and limited experience:
I've produced P. curtus curtus and Borneo's.
>>So, first of all, are you guys incredibly positive that the female is too tired to fight back?
In all cases, the females were defensive, but none ever made a HUGE move to nail me. I believe the concern for the eggs is greater than the defense in most cases and they parry more than strike. I'm sure there are Red Blood keepers with different stories though...
>>I'd also like to ask a few opinions on breeding. I know a lot of publications glorify the blood python as a very simply bred snake, often not requiring any NTL temp changes at all. What are your opinions on that? I personally feel that cooling would be beneficial...as it really cant hurt anything to try. After the cooling period (or not), how do you guys go about the physical breeding?
I cool mine exactly as I do with my Ball Pythons. They are all in the same room and Freedom Breeder rack system.
You can actually read more about it at this link (scroll down the page). It's nearly identical for the Borneo breeding:
http://www.monkeyfrog.com/ballpythondatapage.html
>>I would imagine the female is introduced into the males cage?
The exact opposite here. The male is 'the wanderer', so I only place him in her cage. Never the other way around. I do this with all my snakes.
>> Is there a certain way you should do this? In my experience, the bloods are ALWAYS sleeping, and never moving around. So if you introduce an awake female into a sleeping males cage, does he typically wake right up and start flicking? Or does it typically take hours for courting to occure?
If the male is interested, he will start spurring her immediately. NO delay! The courtship (tail slaps, urinating, spurring) can go on for hours and hours. Eventually, if he's 'lucky' they will copulate. This too can last a while.
>>One last question I always wondered to ask actual hobbyist breeders was; how long do you keep them together? After you put the female into the males cage, do you keep them togther for 3 weeks straight? Or do you separate them after a week to "freshen up" again? Or do you simply wait until the male has lost interest?
I wait until the male is no longer 'resting' on the female. If they are sitting apart, he goes back into his cage for at least 5 to 7 days. Then, back in. Repeat from December until March or whenever they truly show no more interest upon each reintroduction.
Bottom line: ALL bloods are great. My personal favorite are the Borneo. My adults are completely tame (although dangerous at feeding time). Babies are rough around the edges, but calm after a few months of work and wind up just like the parents... tame.
If you don't have any... get some! They are wonderful.
Included is a pic of 'mom' on her 21 eggs (deposited 05/06/05). All the eggs look good so far, so I'm keeping my fingers, eyes and toes crossed!
Hope this helps some...
Matt

-----
"Change what you cannot accept... do not accept what you can't change!"
Tod Ashley C.$.C.