Out there in Florida, many small animal shops do fairly well, unless, as previously stated, you are too close to 'farm land' where an extra 'pet' is unwarranted..
Another thing is that i've seen Pet Shops open and close, and i've seen Reptile Specialty shops add Fish, and then remove them, because they require much too much room and maintenance, and don't bring in enough.
If I were you, I would acquire great variety of small, hardy pets.
Instead of having the normal turtles, iguanas, boas and balls, I would suggest having, let's say, insects, and having many, many different varieties, in their own tiny little 'eco'sphere' display cages..
It would look like it's their own lil world, and it would seem very appealing, especially of how rare they are...
You very well know many of us herpers starting out because we wanted something the other kids didn't have.
So I would have, let's just say, walking sticks, different roaches, different types/sizes of millipedes, 10-20 different tarantula types, 5-10 different scorpion types, and many others i've seen but can't remember at this time.
I would have the wonderful dart frogs, other frogs, atleast 20 different kinds, then lots of Salamanders...
you know how many beautiful Salamanders i've seen in books and always wanted to get but could never find available?
That's the kind of stuff people prize and take care of... ie. spend money on. Not the normal, common stuff that they can get away with neglecting. You get a much more serious hobbyist this way as well.
Scott Feltzer has some outrageous Garter Snakes... colors and patterns I didn't think i'd ever see on a snake...
You can basically 're-invent' the new 'beginner/designer pet'.
Rats have been kept as pets for a long time... They have some breeds and colors that would amaze even those that don't like rats. I had looked for a blue dumbo and a hairless rat before.. never found one. Stock different types of pet quality rats... The typical hamsters and gerbils are dull, boring, 'common', etc... (all you hamster/gerbil lovers, I love them too! just talking about better/newer business strategy here...
)
I think the birds are also too common, not too desireable anymore, and take up space, require maintenance, and make noise and soil their surroundings.
...maybe you can add some other small mammals or marsupials. Sugar Gliders, Mini Foxes, HedgeHogs, Skunks and more.
I also suggest working with different varieties of the Turoises that are becoming popular as of late.
Another point is to specialize in live food. Get as many different types of live food as humanly possible. Not only is this a benefit to you and your customers for the sake of the animals you own and sell, but others will catch on and come from miles away just for the 'best and most natural food' around, and they would have too see your stock, and this can lead to more sales.
So much more....
Most of these things require Marketing, Advertising, Promotions, News Letters, and so on.. these vehicles would only increase your business by a great deal.
I would think you would need this done early, ahead of time. Begin with emailing and creating mailing lists. Perhaps move on to News Letters and advertisements on local classifieds. Then maybe mail out some flyers or something else prior to opening, announcing the grand opening.
Give incentives, like everytime you acrue $100 in purchases with your store, you get 15% off your next purchase, or $15 in store cash. Things like this can attract attention, or help keep clients coming back.
Or you can just hire me to be your store/sales manager... lol
Planned right, I don't see why you wouldn't succeed. If you sit there and wait for them to come to you, you are setting yourself up for disaster... and it may be slow and painful.
Hope that helps!
Take care Jim, Joe Rollo

-----
Thanks and take care - Joe Rollo
'Tis not the stongest of the species that will eventually survive, nor the most intelligent, but the one most responsive to change' Charles Darwin