Hello!
Welcome to the Cham Forum!
I would start by doing tons of research on panther chams and make sure that you have enough space for two 4 x 2 x 2 (minimum) cages with sight lines between them so the chams wont be stressed, a constant supply of a variety of feeder insects, NOT just crix and mealies, the time to mist for a minimum of 30 minutes per day, the money to pay for the electricity they will require, and the fact that you can't handle them much -- they're really "to look at" pets, not "to play with" pets...
If you intend to breed, as you seem to, make sure you get an UNRELATED pair. That doesn't just mean from two different dealers, do your research and KNOW that the parents of both babies are different. We already know the bad results of inbreeding in bearded dragons and leopard geckos, and I would hate to see the beautiful chameleons go the same way. (though veils are started in that direction, as much as i hate to say it...) I would also reccomend that both members of the pair are from the same locality, but that is one of my own personal preferences.
Seeing that you've only kept geckos previously, i would heasitate to reccomend that you get Young chams. I would hope that you would try to get subadults or older juveniles rather than hatchlings, as they will tend to be hardier, rather than very young chams, which are quite fragile, even if they are one of the "hardier" species.
Good luck!
Research research research!!
Jamie