The only thing I would say is the "big" difference is feeding. In my experience even the best eating Green doesn't eat like a Retic. Just be patient. I've had some that would only eat certain prey items, for instance. If you get a quality animal you shouldn't have a lot of problems. Just don't get frustrated if your Green misses a meal here and there. Also, Retics tend to be a little more forgiving as captives to keeper error. Anacondas are a lot less forgiving of a dirty enclosure and tempature requirements. If you have a few years experience under your belt and you are detailed about temperature and cleaning then you should be ready. You just can't be lazy with Greens. I hope this helps.