I would suggest a bearded dragon, especially if you're used to a leopard gecko. They're very friendly, easy to maintain, and you can pick them up and hold them without too much stress on the animal. My boyfriend's beardie is in a forty gallon tank and loves it.

I'm assuming you're thinking lizard again, rather than snake?

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Holly

1.0 Florida Kingsnake (Eddie Gein)
1.0 Bearded Dragon (Charley Manson)
1.0 Fire Skink (Peter Dinsdale)
1.0 Vietnamese Golden Gecko (George Chapman)
0.0.1 Blue Day Gecko (Joe Ball)
1.0 Orange Marmalade Cat (Oliver)
1.0 Black Cat (Shadowfax)
1.0 Tennessee Walking Horse (Durango)

2.0 Toddlers (Justice & Trevor)