Hello, I'd like to know from experts if realistically you get attacked by a crocodile large enough to attack humans as prey, if you realistically have any chance of killing the croc by specifically stabbing or shooting it in it's brain? This is assuming you have a knife or gun in your hand.

Hindrances that come to mind are the obvious violence of croc attacks and if you'd even have a chance with the thrashing you'd be receiving. Also how tough is the crocs skin/skull at it's brain.

Is there any way to kill a croc during an attack?