There are a couple of things you could try but first I would point out that a 75 gallon aquarium is a bit small for that many turtles...especially if the sliders are anywhere near being adults.
You could try feeding some of them (like the muds) in another container or even in a sink. That way, they wouldn't leave any uneaten food around to rot and they will almost always defecate after eating. This eliminates much of the bulk waste.
Also, check the amounts and quality of what foods they are eating. Many times keepers feed mud/musk turtles meaty foods like chicken or beef and these are too greasy for them and foul the water very quickly. I know of others (like myself at times) who give mud turtles pink mice or even larger mice and you can imagine what that does to your filtration system.
If you do offer such things you must first do so SPARINGLY and then make an effort to make these feedings in another container.
This will save you tons of work in the way of water changes and filter cleanings.

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