BlueEyesAtNight,
Is your horned frog an albino specimen? This could explain the pink cloration. (Lack of pigment, more translucet skin). I have also found that some frogs, when sitting in water, seem to develope a pinkish coloration on their underside, this is immediate and fades within an hour or so. You say your frog is still eating, that's a sure sign that he is doing well. As for a lack of activity, all horned frogs are squat, fat, and "lazy". Their idea of a nice life would be to sit wait for food, eat the food, sit some more, poop, and move (then repeate the whole process over again till kingdom come). So don't be concerned by the lack of movement. As for changing the substrate, these frogs eat a lot, and thus produce large amounts of excrement when they deficate. This is hard to miss, and if removed in a timely manner, sums up all the cleaning that needs to be done for them. If you're changing the all the bedding once a month you'll be just fine. Just make sure the water is always clean and fresh. As far as a possible infection goes, if he has had the coloration for a long time (say two weeks or more) it is almost surely not an infection as by this time he would have expired. If you're keeping his cage damp and clean there should be no problem. If it is an infection, more frequent cage cleanings will do little to supplement recovery, as it will most likely not go away on its own. Most amphibian infections are caused by poor husbandry (which doesn't sound like an issue here) and present some kind of small reddish sores on the underside of the frog. You'll have to see a vet who works with amphibians. But again doesn't sound like an illness. If you can, post the picture it will clear up any questions. Best of luck to you and your frog.

EMWhite

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