Obviously every gecko is different, and they all have unique personalities, so your mileage may vary. Mine started out super flighty, basically running away all the time. This led to us not handling her as much as we would like to because it was stressful for us and her. Even with handling her only infrequently, she became much more calm and handleable as she got older. She's still not tame to the level of my leopard gecko, who will climb up onto your hand of her own free will, but she is *much* calmer than she used to be. I'd say as long as you feel like you can keep control of the situation, handle her 1-2 times a week and she'll probably reach the point where she's comfortable with it sooner than mine did. At this point, mine resists coming out of her enclosure, but once she's out, she's basically well behaved, not seeming to be overly stressed by it.
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0.1 Albino Leopard Gecko - Tigger

0.1 Crested Gecko - Pooh-Bear

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