Siamese are notoriously territorial. Does Dusty attack your grandmother? If not, then Dusty just may be trying to claim her as his, and trying to drive you (the interlopers) off. Or Dusty may be sensing another cat (perhaps your kitten has left some scent on you) and is attacking for that reason.

Dusty should probably be fully evaluated by a vet and possibly and animal behaviorist. An extremely aggressive cat is no joke and can really do damage to a human. If he is doing this to people who visit your grandmother, it needs to stop.
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Smile, it will make them wonder what you are up to!

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