This is pretty normal, I wouldn't worry at all.

I have two brother cats from the same litter that are now 14 years old. They are inseperable.

Whenever one goes to the vet without the other, when they get back together, I have a few hours of hissyness and growls, primarily due to smells.

Last year, Pookey had to have his rear leg amputated due to cancer (from a rabies shot). Stanley avoided him for the better part of a week. He was very careful around him and stayed clear of him. They didn't get back to normal for about two weeks. Pookey needed a lot of care and I think Stanley sensed that. There was some light hissing, but primarily, they kept their distance for several days...

What your two are going thru sounds perfectly normal. Give it a few days, at most, and they'll be back to normal.
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Tammy
Stanley and Pookey

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